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Yes, I have been taking the full-size (325mg) aspirin for decades with no GI tract problem (but I have been known to have a "cast iron stomach"). My wife has been taking the smaller dose. I understand aspirin is also supposed to help reduce the occurrence of various cancers and maybe even Alzheimer's. My recent checkup resulted in an A+ health rating so I will continue the full-size - with my doctor's approval of course.

Besides lots of raw veggies and a lot of activity, I also recommend using a WaterPik nightly but with straight Listerine instead of water. I credit this with avoiding cavities and even colds for many years.

Stay healthy!