TexasCHLforum.com

I asked the folks at Capitol Armory if there would be an issue shooting.22 LR out of a 9mm can. The response was that it would be okay to shoot a little bit of .22 LR out of it, but because most .22 LR is lead (ie, not copper jacketed) that shooting extensive amounts would eventually cause lead deposits to fill up the insides & ruin it. ((The suppressor in question has an end cap that can be changed, but it can't be disassembled to clean the baffles & housing)).

The BLUF as I recall was damage from lead fouling was not likely to occur with just hundreds of rounds; it was more like if you use a 9mm can that you can't disassemble (to clean the baffles) as a dedicated .22 suppressor for tens of thousands of rounds, or something like that.