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A Glock with a round in the chamber is no different than a double action revolver. Both go bang if you press the trigger. Of course, the trigger pull on a Glock is usually less than a wheelgun, but you get the point.

One of the reasons I like my XD over a Glock is the grip safety. No manual safeties to manipulate in order to fire the pistol, but, as least for me, that grip safety is very reassuring (knowing it must be activated by a proper grip along along with the trigger safety when pressing the trigger). I also love my little 642 snubbie in a pocket holster. As others have said, I'm entirely comfortable as long as the trigger is covered by a proper holster (pocket or hip).

Cheers