We have "nightstand" style safes designed for securing a pistol in our vehicles. They have a cable attached to them and the other end locks around the seat frame.
Please note I'm aware it would be possible for someone to unbolt the seat, etc. but that takes time that your average smash and grab thief doesn't want to spend. I'm not looking for a debate here just sharing for those that are interested.
My point is that rather than adjust a holster everytime I'm getting in or out the car or truck I've got a dedicated pistol for each vehicle.
The only time the pistol goes in the safe is when the vehicle will be parked out of sight for any length of time - otherwise it's stashed in a spot that it can be grabbed in an instant, but not in a manner thats obvious from outside (like between the seats with the grip sticking up slightly and covered with a washcloth).
My personal experiance is that this provides a much smoother entry and exit, and considering some of the most recent bad guy tactics involving attacking their victims either upon exit or entry of a vehicle I think this might shave off a few cruical moments off of getting a gun in your hand when you really need it.
Of course this is just my humble opinion, I don't claim to be an expert, just a fellow CHL holder who refuses to be a victim.
Of course some of those side mounted flame throwers would be nice too
