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Well I carry a .380 Bersa and I don't feel underpowered but shot placement really really matters. My father's friend was robbed at gun point a few months ago and shot in the stomach with a 9mm once. He said at no time was he unable to move. The most crippling thing was the pain. He said it is indescribable!!! Granted if he was shot in the chest it would have been a different story but the only time he lost conciseness was when the ER put him under for surgery. I know there are many so called tests on stopping power. What I can tell you is that from personal experience a 10mm, .357 mag to a deer or large boars chest area is in my experience a one shot stop and quickly at that. A 45 will usually drop them fast to but sometimes they move a few feet and then drop. All of these bullets didn't just stop the animals but killed them within a few seconds. Shot placement is still the most important thing but if a 10mm, .357 or .45 is enough for a thick muscle wild boar or deer with a thicker hide then a human then its enough for me to carry with the idea that I put the bullets in the chest or head. Just my 2 cents.