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It all depends on what you are shooting...FMJ for target or plinking...JHP for self defense.

The following web link will answer many questions about what a JHP bullet will do to a human body. This expert study shows what a JHP will do in ballistic gelatin, which is designed to mimic the human body. This is about as good a scientific answer as you will get without an autopsy.

http://ammo.ar15.com/project/Self_Defen ... /index.htm" onclick="window.open(this.href);return false;

This is found on the AR15.com web site, in their forums area. For you high-velocity (+P) fans, the slow-poke (.40 & .45) rounds are proven to penetrate deeper and render more damage...sorry.

If my objective in self defense is to stop the BG, I want to make sure that the objective is achieved in as few shots as possible. A FMJ is far less likely to stop a BG, and certainly not as efficiently as a JHP will.

I hope this answers your question...