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My experience with the larger hogs is that anything .223 or smaller is insufficient unless you are getting excellent shot placement like Abraham implied above.

I once filled a large hog (maybe it was a small hippo?) with .223 rounds aimed at the chest area and it danced off into the woods never to be seen again. Another time it took about 5 shots with the 30-30 to bring one down. Like The Annoyed Man, I now keep an M1A around for hogs.