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I think the Lee hand prime is hard to beat. The Lee prime on the press setup is a little slow, and hard to get a good feel for primer seat depth, so I use the hand prime. Lee has another setup for priming on press where the case is place on top of the press. Lee Prime II?

RCBS has 2 hand prime, one uses universal case holders, the other doesn't.

RCBS APS primer is supposed to be the safest.