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I settled on the 40 after a lot of research and looking into. IMHO the 40 does everthing a 45 can do, but usually at a higher capacity, and is a little more effective than a 9x19. That being said, any round, including a 22-RF would do the job if it hit the eye socket - so location is still supreme. The 40 does have a sharper recoil than a 9x19 and about equal to a 45 IMHO. On the other hand Gabe Suarez has gone exclusivly to the 9x19 for capacity reason I believe. He doesn't seem to feel under gunned with the 9x19.