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I have only one currently that I would readily sell to help fund the purchase of a higher quality replacement. It runs fine, but is one of the few guns I bought more or less on a whim. It is a Chiappa 1873-22, which will hopefully one day be replaced by a Ruger Single-Six or Single-Ten. Other guns I have sold for a variety of reasons include:

Remington 572 to fund the acquisition of a 10/22
Ruger Super Blackhawk Stainless 10.5" in .44 Mag. -- Sold since I wasn't planning on participating in IHMSA anytime soon.
Remington 740 in 30-06 with Weaver K4 scope, Sold because it did not really fit a niche for me after I acquired a Ruger GSR .308
SIG 1911-22, sold to a 1911 guy and replaced by a S&W M&P 22
Beretta Neos, sold to a lady who appreciated the small grip more than I did
Smith and Wesson 659, sold when we moved to standardize on striker fired semi-autos (with less blocky grips and lower weight)
Smith and Wesson 22A, sold to a young shooter who found the grip much more to his liking than I did
Smith and Wesson Shield, sold when replaced with a similar gun with aftermarket trigger
Smith and Wesson 325PD, sold because our defensive handguns were generally coalescing on the striker fired semi-auto platform
Stevens 350, sold as redundant to the Remington 870s we have, and the bottom feed/ejection is not as flexible if having to load singles in a pinch.

All the firearms we have are shooters, so really any of them are for sale at any time if the price is right. Many of them might require higher than market value to purchase, though, since we'd likely want to replace them with something very similar in short order and time is money.