Dragonfighter wrote:Elitist Mac users...sheesh

. For those of us STILL in the PC world the best thing I have ever seen, for deep scan and removal even from boot sectors is
Combofix. I keep a copy of that and a sundry list of a few other tools on my flash drive to help friends out when they have a problem. It creates a restore point and "recovery mode" boot option within your Windows installation. I have never encountered a rootkit or other boot sector virus it couldn't eradicate. Kind of a nuclear option.
I am very careful as the rest of my family is, I use AVG as well as Spybot in combination and so on. But just in case I keep a rescue disc, written in Linux with all of my other "weapons" on it. I have rebuilt at least one boot sector with it.
All work of my own is done on Macs... But I work on Macs and Windows for pay.

I've seen some nasty root kits just recently. Modifications of older stuff (ransomware), but they don't seem to be doing what was intended (demanding money

); they just screw up the machines and invite more friends to the party.
Here's what I use:
Spybot Search and Destroy
Malwarebytes AntiMalware (they also have an anti rootkit package that's still in beta)
Combofix
TDSSKiller
Hitman Pro
Other software as needed.
Windows users, do youselves a favor: buy a Malwarebytes lifetime license for $24.95. It actively scans and monitors outgoing traffic, blocking attmpets to contact known-to-be-bad sites. Run it along with good antivirus software.
The best is antivirus software is ESET, either their antivirus only product, or Smart Security (antivirus, antimalware, antispam, firewall...).
A customer just switched (against my recommendations) from ESET to Norton Internet Security to save $1/year/machine...

And have had to pay me more than they'll save in years to get everything working with Norton.